Risk factors for recurrence of benign convulsions with mild gastroenteritis in children: A prospective cohort study
Abstract
‘Benign convulsions with mild gastroenteritis’ (CwG) are defined as convulsions in children with viral gastroenteritis in the absence of severe dehydration, electrolyte or metabolic disturbances. Although first reported by Morooka et al. in 1982, the pathogenesis and course of CwG is still not well-defined. To date, CwG is not formally recognised by the International League Against Epilepsy. However, it is generally considered to be a benign situation-related seizure rather than epilepsy. As the convulsions in the acute phase are often clustered seizures, it can lead to anxiety for both the parents and the treating physician. Despite the good prognosis, studies have shown a varying percentage of seizure recurrence (0–20%) in CwG. Identifying risk factors for seizure recurrence can help in proper management and follow-up. The aim of our study was to identify risk factors for the recurrence of CwG in children from the initial onset of CwG. We prospectively reviewed the medical records of children admitted for CwG in a tertiary teaching hospital over a five-year period (Jan 2011-December 2015). The inclusion criteria were identical to those described in previous studies: (i) children aged 6 months to 3 years of age; (ii) mild gastroenteritis with afebrile convulsions, no or mild dehydration, normal metabolic and electrolyte panel; and (iii) normal neuroimaging, electroencephalogram (EEG). We excluded cases with developmental disorders, epilepsy, encephalitis, meningitis,…
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