To findout impact and effectiveness of rotavirus vaccine (RV5) on acute gastroenteritis (a study of 79 case)

Ajaysinh.V Jadeja, Bhadresh Vyas, Maulik Mangroliya

International journal of scientific research, 2023

Abstract

This is a prospective – observational study, hospital-based surveillance for acute gastroenteritis (AGE) conducted for period of November 2020 to February 2021. Total 100 cases of AGE < 5 years of age admitted at G.G.H Jamnagar, pediatric department in period between November 2020 to February 2021. Out of 100 cases, 79 cases 8 weeks to 2 years of age group enrolled in study for Case-control evaluation according to inclusion and exclusion criteria. Level of Dehydration determined on Admission according to IMNCI Guideline. A case-control evaluation method will be used to evaluate the effectiveness of RV5 (Rotasiil) in the 8 weeks to 24-month-old participants. Vaccination information collected from Mamta card/ vaccination card. Severity of AGE plotted against Rota vaccinated and Un vaccinated Group followed by CHI SQUARE Test applied which shows 2 =7.58 and p value = 0.02 which is statistically signicant, which indicating that Rota Vaccine having Less major Impact on Mild to Moderate AGE, whereas there is denitive decrease in severe AGE cases among the rota vaccinated children

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Evidence Hub reads this as a case-control, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.

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