Immunization Patterns of Children with Chronic Neurological and Neurodevelopmental Disorders: A Cross-Sectional Study from Istanbul
Abstract
Highlights What are the main findings? Partial vaccination was substantially more common than complete vaccine refusal among children with chronic neurological and neurodevelopmental disorders. Vaccination completeness and the age period after which routine immunization was discontinued differed significantly across diagnostic groups. What are the implications of the main findings? Incomplete immunization in children with chronic neurological and neurodevelopmental disorders appears to follow diagnosis-specific patterns rather than a uniform trend. Assessing vaccination continuity may help support diagnosis-sensitive immunization counseling during pediatric neurology follow-up. Abstract Background/Objectives: Children with chronic neurological and neurodevelopmental disorders (CNDD) constitute a medically vulnerable population in whom routine childhood immunization may be interrupted because of clinical complexity and parental concerns. This study aimed to evaluate immunization patterns, timing of vaccination interruption, and associated clinical and sociodemographic factors in children with CNDDs followed at a tertiary pediatric neurology center. Methods: This prospective cross-sectional study included 545 children aged 1–18 years with chronic neurological and neurodevelopmental disorders evaluated between September and November 2025. Immunization status according to the Turkish National Immunization Program was classified as fully vaccinated, partially vaccinated, or not…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 545 participants or records.
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