The Atopic Diseases in Children Having Eosinophilic Gastroenteritis
Abstract
Background: Eosinophilic gastroenteritis is a chronic antigen mediated inflammatory disease that may occur in any part of the intestine, with a significant increase in the incidence in the last years. It might correlate to the increasing in atopic diseases. Materials and methods: An Observational Descriptive study (Case series) was conducted in 57 children with eosinophilic gastroenteritis. They are selected from Pediatric Gastroenterology Clinic, Tishreen University Hospital between September 2016 and September 2021. Results: A total of 57 children, 38 males (66.7%) and 19 females (33.3%) were included in the study. The median age was 5 years, and the most frequent age group was ≤ 3 year (43.9%). Growth failure (45.6%) and abdominal pain (29.8%) represented the most frequent clinical complaints. Many parts of the gastrointestinal tract were affected, and duodenum was the most affected part (63.2%), followed by duodenal bulb (8.8%), colon (5.3%), esophageal (3.5%), and stomach (3.5%). Family history of atopic diseases was present in 29.8% of the cases, especially in both parents (15.8%). The most common atopic features were asthma (36.8%) and allergic rhinitis (31.6%). Milk represented the most frequent food allergen (10.5%), which was diagnosed according to clinical history and food intolerance tests with presence of a significant correlation between food allergy and histological findings (p: 0.02). There were significant differences of the atopic features according to the…
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health. Reported size: 57 participants or records.
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