Full tablet and half tablet empagliflozin prescription demographic and glycemic control
Abstract
INTRODUCTIONSodium-glucose co-transporter 2 (SGLT2) inhibitors prescription has been given greater emphasis in recent years, and it has been adopted as a first-line or secondline treatment in major international guidelines. In the public practice of the Ministry of Health hospital, the main SGLT2 inhibitor prescribed is empagliflozin. However, the prescription is still limited by cost despite efforts to increase prescription. The practice of prescribing half tablet empagliflozin (12.5 mg) has yet to be recommended but has been widely practiced in many centres in Malaysia. There is no evidence advising for or against this practice. Hospital Sultan Haji Ahmad Shah (HoSHAS), a tertiary hospital in Central Pahang, has initiated a prescription of half a tablet of empagliflozin (12.5 mg) in 2019. An assessment of this empagliflozin prescription pattern and its effects on glycemic control is essential to inform future prescription direction.
METHODOLOGYThis cross-sectional study was conducted in HoSHAS, a tertiary hospital in Temerloh, Pahang, Malaysia, in March 2023. All patients on treatment were included in the study. Electronic medical records were reviewed for patient demographic data and glycemic control at initiation, and the latest follow-up data were collected. The study aimed to determine the demographic profile of patients on empagliflozin and the difference in glycemic control between full-tablet empagliflozin (25 mg) and half-tablet empagliflozin (12.5 mg) in this…
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