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Physicians Experience with SGLT- 2 Inhibitors In Type 2 Diabetic Patients

Zainab Aqeel Khan, Umaimah Muzzamil, S. F. Jawed, Wajid Ali

Annals of King Edward Medical University, 2025

Abstract

Background: Approximately, 104 (55%) physicians reported hypertension (HTN), obesity, chronic kidney disease (CKD) and hyperuricemia as the most prevalent comorbidities in diabetic patients.

Objectives: This study investigates the experience of Pakistani physicians regarding the use of Sodium-glucose Cotransporter-2 (SGLT2) inhibitors in the management of Type 2 Diabetes (T2D).

This cross-sectional survey study was conducted from 1st October to December 31st, 2023, enrolled 189 physicians.

Methods: The data was collected by self-administered structured questionnaire which was distributed among physicians across various specialties involved in diabetes care, assessing their views on the efficacy, safety, and economic considerations of SGLT2 inhibitors.

Results: Approximately, 104 (55%) physicians reported hypertension (HTN), obesity, chronic kidney disease (CKD) and hyperuricemia as the most prevalent comorbidities in diabetic patients. Empagliflozin was the most prescribed among SGLT-2 inhibitor in patients with heart failure. Approximately, 50% of the physicians advise SGLT-2 inhibitor frequently to their patients. Approximately, 81% of the physicians considered efficacious medicine with cost- benefits for their patients and also 89% of them agreed that the cost and quantity of daily diabetes medications impact a patient's overall diabetes management.

Conclusion: The study emphasizes the importance of addressing these economic challenges to enhance the accessibility and…

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