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Efficacy of Potassium-competitive Acid Blockers versus Proton Pump Inhibitors in First- and Second-line Eradication Regimens for Helicobacter pylori in Egyptian Patients

Noor Al Deen A. Elazazi, Mohamed Mahmoud Eltabbakh, Hend Mubarak Hussein, Yasmeen Mahmood, Reda Elwakil

Journal of Translational Gastroenterology, 2024

1 citation

Abstract

The treatment of Helicobacter pylori (H. pylori) infection remains a challenge due to the increasing prevalence of drug-resistant bacteria. It is hypothesized that using more potent acid suppressants, such as potassium-competitive acid blockers (P-CABs) like Vonoprazan, may improve eradication rates. The aim of this study was to compare the effectiveness of H. pylori eradication regimens containing Vonoprazan with those containing proton pump inhibitors for H. pylori infection.

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