Lifestyle risk factors, inflammatory mechanisms, and COVID-19 hospitalization: A community-based cohort study of 387,109 adults in UK
Abstract
Highlights • The association between lifestyle factors and risk of COVID-19 hospitalisation is unknown.• Poorer lifestyle habit and elevated C-reactive protein was associated with greater risk of COVID-19 hospitalisation.• Unhealthy lifestyle behaviours in combination accounted for up to 51% of the population attributable fraction of severe COVID-19.• Low grade inflammation may be an important mechanism.• Adopting simple lifestyle changes could lower the risk of severe COVID-19 infection.
How strong is the evidence?
Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence.
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