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Risk of Cardiovascular Events in Patients with Primary Biliary Cholangitis - Systematic Review

Duminda Suraweera, Christina Fanous, Melissa Jimenez, Myron John Tong, Sammy Saab

Journal of Clinical and Translational Hepatology, 2018

34 citations

Abstract

There is not enough evidence to suggest an increased risk of cardiovascular disease in patients with PBC with hypercholesterolemia, except for those individuals with concomitant features of metabolic syndrome. In patients with PBC with no additional cardiovascular risk factors, individual risk/benefit discussion on lipid-lowering treatment should be considered.

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Evidence Hub reads this as a systematic review, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.

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