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Empagliflozin-Associated Pancreatitis: A Consideration for SGLT2 Inhibitors

Dziadkowiec KN, Stawinski PM, Proenza J

ACG case reports journal, 2021

Abstract

Empagliflozin belongs to a class of sodium-glucose cotransporter-2 inhibitors, a medication approved by the US Food and Drug Administration in 2014 for the treatment of type 2 diabetes mellitus. Well-known side effects of this medication include symptomatic hypotension, hypoglycemia, and urinary tract infections among others. We present a case of severe epigastric abdominal pain consistent with acute pancreatitis in the setting of empagliflozin use, suggesting a possible drug-induced acute pancreatitis.

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