HoLEP vs TURP in Benign Prostatic Hyperplasia: A Systematic Review
Abstract
Purpose: This review evaluates the efficacy, safety, and durability of HoLEP versus TURP, addressing the research gap concerning their comparative long-term stability and performance across varying prostate volumes. The study focuses on functional outcomes, complication profiles, and the scalability of each technique.
Research Methodology: A systematic search (2020–2025) identified RCTs and meta-analyses comparing HoLEP and TURP in BPH patients. Parameters analyzed included IPSS, Qmax, PVR, perioperative outcomes, and reoperation rates.
Results: Both procedures show comparable functional gains. However, HoLEP offers a superior perioperative profile, significantly lower bleeding risk, and higher long-term durability. Furthermore, HoLEP’s efficacy is independent of prostate size, whereas TURP efficiency diminishes in larger glands. Conclusions: Despite a steeper learning curve, HoLEP’s safety and versatility position it as the primary modern surgical standard. TURP remains a relevant alternative depending on institutional facilities.
Conclusions: Despite having a longer learning curve, HoLEP is worthy of consideration as the primary choice in modern surgical management of BPH, while TURP remains relevant in certain conditions and facilities.
Limitations: Limitations of this systematic review are the heterogeneity of study designs, populations, and follow-up durations, which may affect the comparability of results.
Contributions: This review provides a contemporary…
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Evidence Hub reads this as a systematic review. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.
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