A controlled clinical trial to evaluate the efficacy of Tilanala Kshara in the management of Vatashteela vis-a-vis Benign Prostatic Hyperplasia
Abstract
Background: Benign prostatic hyperplasia is the most common urological disease among elderly men, which is characterized by hypertrophic nodular changes of the prostate gland, which is located at the base of the bladder surrounding the proximal urethra. Gland grows at the rate of 2.4cm3/year after the age of 40 owing to the change in hormonal environment. In India, the prevalence rate is around 50% in men above the age of 65 years. The condition can be corelated to Vatashteela in Ayurveda based on the symptomatology. Objective of the study: To evaluate the efficacy of Tila Nala Kshara in the management of Muthraghata vis-a-vis BPH. Materials and Methods: A double arm open labelled clinical study with pre-post-test design was carried out at Government Ayurveda Medical College and Hospital, Mysuru. Data was collected as per the proforma prepared for the purpose of the study. Tila Nala Kshara was administered as intervention in 54 subjects and the control drug was Gokshuradi Guggulu. The data was analysed using SPSS descriptive and inferential statistics. Results: Among the objective parameters, change in prostate volume was significant between the groups with a P value 0.024. But for postvoid residual volume, the difference between the groups was not statistically significant. For subjective parameters which includes IPSS total and Quality of life scale, the difference between the groups was statistically nonsignificant. Conclusion: Tilanala Kshara when used along with…
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