Effect of biofeedback electrical stimulation combined with HoLEP on surgical outcomes in patients with benign prostatic hyperplasia complicated with detrusor underactivity: a retrospective cohort study
Abstract
Objective To investigate the clinical efficacy and safety of biofeedback electrical stimulation combined with holmium laser enucleation of the prostate (HoLEP) in the treatment of patients with benign prostatic hyperplasia (BPH) complicated by detrusor underactivity (DUA). Methods A retrospective analysis was conducted on 100 patients with BPH and DUA who had surgical indications and were treated in the Department of Urology of our hospital from January 2023 to June 2025. Patients were divided into an intervention group (n = 51) and a control group (n = 49) according to the treatment modality they received. Patients in the intervention group underwent HoLEP followed by biofeedback electrical stimulation therapy (three times per week for a total of 10 sessions), whereas those in the control group received HoLEP alone. The International Prostate Symptom Score (IPSS), Quality of Life score (QOL), maximum urinary flow rate (Qmax), bladder contractility index (BCI), bladder outlet obstruction index (BOOI), maximum detrusor pressure (Pdetmax), post-void residual volume (PVR), voiding efficiency (VE), and postoperative complications were compared between the two groups before surgery and at 3 months postoperatively. Results Baseline characteristics were comparable between the two groups (P > 0.05). At 3 months postoperatively, the intervention group showed significantly higher Qmax (14.38 ± 1.47 mL/s vs. 10.01 ± 0.85 mL/s, P 0.05). Conclusion Biofeedback electrical stimulation…
How strong is the evidence?
Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 100 participants or records.
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