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0905 Effects of Benign Prostatic Hyperplasia Surgery on Positive Airway Pressure Therapy Compliance in Sleep Apnea

Stephanie G. Wong, Alan Quach, Christopher M. Deibert, John J. Harrington

Sleep, 2024

33 participants

Abstract

Despite the high efficacy of continuous positive airway pressure (CPAP) to reverse the upper airway obstruction in obstructive sleep apnea (OSA), one of the greatest barriers to treatment is CPAP nonadherence. Benign prostatic hyperplasia (BPH) is a common diagnosis among the ageing male population that causes lower urinary tract symptoms (LUTS). Nocturia results in nighttime awakenings which may interfere with CPAP adherence. There are a variety of surgical interventions for the BPH. The aim of this study is to assess CPAP adherence rates before and after surgical intervention for treatment of BPH.

A within-subject retrospective analysis was performed at a single institution. Thus far, a sample size of 33 patients were analyzed and 16 met inclusion criteria. The target cohort included male patients who have a diagnosis of OSA and underwent surgical intervention for BPH between October 2013 and October 2023. The subjects included were also started on positive airway pressure (PAP) therapy before surgery. CPAP adherence measures were obtained one to six months prior to surgical intervention and compared to CPAP adherence measures six months post-surgical intervention. The change in PAP compliance from before surgical intervention to six months after surgery will be calculated and compared to a null value of zero (ie, no change) using a paired t-test.

The average age of patients was 69.3. BPH procedures included were transurethral resection of the prostate (TURP) (37.5%),…

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