Comparative Analysis of Greenlight Laser Photovaporization and Holmium Laser Enucleation of the Prostate for Benign Prostatic Hyperplasia Surgery
Abstract
OBJECTIVE
This study aims to compare efficacy and safety between photoselective vaporization of the prostate (PVP) with Green- Light laser and Holmium laser enucleation of the prostate (HoLEP).
MATERIALS AND METHODS
A total of 220 patients who underwent endoscopic disobstruction surgery of the prostate were included; Of which, 110 had PVP and 110 had HoLEP (prospective cohort). Preoperative, intraoperative and postoperative variables were recorded, including hospital stay, catheterisation duration, adverse effects, transfusion rate, maximum urinary flow (Qmax) at 12 months, reduction of prostate-specific antigen (PSA) at 6 months, urgency, urinary continence and urethral stricture. Statistical analysis was performed with Fisher's exact, Student's t and Mann-Whitney U tests, with a significance level of p < 0.05.
RESULTS
Both groups presented comparable preoperative characteristics. No significant differences were observed in the days of admission, days of catheterisation, adverse effects, transfusion rate or readmission rate. However, the HoLEP group showed a significantly higher Qmax (31.31 mL/s vs. 24.48 mL/s, p = 0.014) and a greater reduction in PSA (94.54% vs. 47.11%, p = 0.008). Urgency was lower in the HoLEP group (0.9% vs. 11.8%, p = 0.001), and the rate of urinary continence was identical in both groups (99.09%). Urethral stricture was higher in the HoLEP group (4.5% vs. 0.9%, p = 0.219), although the difference was not statistically significant (p > 0.05).…
How strong is the evidence?
Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 220 participants or records.
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