CHRONIC VISCERAL PAIN TREATED WITH 10 khz SPINAL CORD STIMULATION: A CASE REPORT
Abstract
INTRODUCTION Visceral pain originates from thoracic, abdominal, or pelvic organs. It is typically diffuse, poorly localized, and described as cramping, pressure-like, or deep aching1. Pathophysiology involves activation of unmyelinated C fibers due to mechanical distension, ischemia, or inflammation. Signals are transmitted via autonomic pathways to the CNS. A key feature is spinal convergence of visceral and somatic afferents, resulting in referred pain. Autonomic symptoms (e.g., nausea, sweating, tachycardia) and strong emotional components are also common, due to limbic system involvement. Diagnosis and management are often complex, requiring multimodal approaches. CASE PRESENTATION A male patient was referred for chronic right hypochondrial pain. History included benign prostatic hyperplasia, right radiculopathy, and left coxalgia, previously treated with infiltrations. The patient reported 10 kg weight loss due to pain. Ongoing medications included buprenorphine patch (52 mcg/h), oxycodone/naloxone (20 mg TID), pregabalin (75 mg BID), duloxetine (30 mg daily), and vaporized high-THC cannabis (four times/day). Pain began eight years earlier, described as constant stabbing in the right hypochondrium, alleviated by walking and worsened by sitting. Flares improved with intramuscular diclofenac. MRI revealed right renal inflammatory changes; PET showed somatostatin receptor uptake in the duodenopancreatic area. Lumbar MRI was normal. Given the diagnosis of drug-resistant…
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Treatment of non-metastatic castration-resistant prostate cancer: facing age-related comorbidities and drug–drug interactions
- The Efficacy of Flogofilm® in the Treatment of Chronic Bacterial Prostatitis as an Adjuvant to Antibiotic Therapy: A Randomized Prospective Trial
- Inhibition of growth and contraction in human prostate stromal cells by silencing of NUAK1 and -2, and by the presumed NUAK inhibitors HTH01-015 and WZ4003
- Effectiveness and Safety of a New Nutrient Fixed Combination Containing Pollen Extract Plus Teupolioside, in the Management of LUTS in Patients with Benign Prostatic Hypertrophy: A Pilot Study
- Extract from Cucurbita pepo improves BPH symptoms without affecting sexual function: a 24-month noninterventional study
- Aquablation vs. holmium laser enucleation of the prostate for benign prostatic hyperplasia: a 150-patients prospective comparative multicenter study
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.