Tadalafil therapy in symptomatic improvement of LUTS due to BPH and associated Erectile Dysfunction
Abstract
1 Prof., 4,6,7 Junior Resident, Dept of General Surgery, Indira Gandhi Medical College, Shimla, HP 171001 2 Associate Prof., 5 Senior Resident, Dept of Urology, Indira Gandhi Medical College, Shimla, HP 171001 3 Associate Prof., Dept of Community Medicine, Indira Gandhi Medical College, Shimla, HP – 171001 Corresponding Author Dr Rishi Nabh Email: [email protected]. Phone No. 7018614647 Abstract Introduction: Benign prostatic hyperplasia, one of the most common urological problem in aging man, is a complex disease and is often associated with bothersome LUTS. Objective: The aim of present study was to assess the efficacy of Tadalafil 5mg once daily in symptomatic improvement of LUTS and erectile function in patient’s with comorbid BPH and ED. Material and Methods: 34 patients of bothersome LUTS with IPSS>8, Qmax <15 were treated with Tadalafil monotherapy 5mg once daily for a period of 12 weeks. Observations: Tadalafil therapy (5mgonce daily) resulted in clinically meaningful and statistically significant improvement in LUTS secondary to BPH. Tadalafil improved IPSS, Qmax, PVRU and quality of life index. Statistically significant improvement of IIEF score (mean change; 3.735±1.082) at 12 weeks was observed (p<0.001). Conclusion: Tadalafil seems to be promising treatment option for patient’s with LUTS secondary to BPH and associated ED. Keywords/Abbreviations: LUTS– Lower Urinary Tract Symptoms, PVRU–Post Void Residual Urine, ED– Erectile Dysfunction, IPSS – International…
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