Inhibitory effects of Calocybe indica macrofungi on experimental benign prostatic hyperplasia in rats
Abstract
Objectives: extract on testosterone-induced benign prostatic hyperplasia in rats. Materials and Methods: extract while one group was administered finasteride as the standard drug and the other left as untreated BPH model group given testosterone propionate only. BPH in the prostate gland was detected through gross appearance, prostate weight, and biochemical and histopathological analyses. Results: extract led to a reduction in prostate weight, prostatic index, serum PSA, serum levels of testosterone, and prostatic epithelial thickness, and increased luminal diameter. Conclusion: mushroom is a potential pharmacological candidate for the management of BPH in man or dogs.
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