The correlation of metabolic syndrome with the natural history of benign prostatic hyperplasia
Abstract
Benign prostatic hyperplasia (BPH) is one of the most common conditions affecting the male urinary system, primarily affecting men over the age of 50.While the exact etiology of BPH is not fully understood, several risk factors are associated with its development, including age, genetic predisposition, hormonal changes, and inflammation.On the other hand, metabolic syndrome (MS), characterized by the coexistence of hypertension, elevated fasting glucose, increased waist circumference, dyslipidemia, and insulin resistance, has been recognized as a significant risk factor for cardiovascular diseases and type 2 diabetes.Over the past decade, numerous studies have attempted to investigate the association between metabolic syndrome and the development and progression of BPH, aiming to understand the mechanisms that may link these two conditions.This thesis analyzes this association, focusing on the potential pathophysiological mechanisms and the clinical implications of the interaction between these two conditions.It concludes with an exploration of possible therapeutic approaches for managing both diseases, ultimately contributing to the improvement of the overall quality of life for patients.
Read the paper
Related studies
- Treatment of non-metastatic castration-resistant prostate cancer: facing age-related comorbidities and drug–drug interactions
- The Efficacy of Flogofilm® in the Treatment of Chronic Bacterial Prostatitis as an Adjuvant to Antibiotic Therapy: A Randomized Prospective Trial
- Inhibition of growth and contraction in human prostate stromal cells by silencing of NUAK1 and -2, and by the presumed NUAK inhibitors HTH01-015 and WZ4003
- Effectiveness and Safety of a New Nutrient Fixed Combination Containing Pollen Extract Plus Teupolioside, in the Management of LUTS in Patients with Benign Prostatic Hypertrophy: A Pilot Study
- Extract from Cucurbita pepo improves BPH symptoms without affecting sexual function: a 24-month noninterventional study
- Aquablation vs. holmium laser enucleation of the prostate for benign prostatic hyperplasia: a 150-patients prospective comparative multicenter study
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.