Global research landscape of natural medicines for lower urinary tract symptoms: bibliometric and clinical trial analysis
Abstract
BACKGROUND: Natural medicines have demonstrated significant therapeutic potential in the management and attenuation of lower urinary tract symptoms (LUTS). According to the Web of Science Core Collection (WoSCC), a total of 497 related articles have been published during the last 25 years. China was the most productive country, followed by India and the United States. However, the United States showed substantial influence in earlier years and contributed prominently to clinical trial activity. This study employs a systematic, visualized synthesis of bibliometric and clinical trial data to effectively delineate the research frontier and inform future directions. METHODS: To map the research landscape, a bibliometric examination was performed using a structured search query to gather relevant papers on natural medicines and urinary symptoms published over a 25-year span. The information extracted for analysis included titles, journals, authors, affiliations, citations, keywords, and a set of keywords associated with natural medicines for urinary symptoms. Furthermore, the ClinicalTrials.gov registry was utilized to evaluate the profile of trials testing natural agents against LUTS. RESULTS: The bibliometric analysis included 497 publications from 78 countries and identified a total of 22,160 cited references. China produced the highest number of publications. Review of the clinical trial data indicated that most trials were conducted in phases II-IV. Research activity in this…
Read the paper
Related studies
- Treatment of non-metastatic castration-resistant prostate cancer: facing age-related comorbidities and drug–drug interactions
- The Efficacy of Flogofilm® in the Treatment of Chronic Bacterial Prostatitis as an Adjuvant to Antibiotic Therapy: A Randomized Prospective Trial
- Inhibition of growth and contraction in human prostate stromal cells by silencing of NUAK1 and -2, and by the presumed NUAK inhibitors HTH01-015 and WZ4003
- Effectiveness and Safety of a New Nutrient Fixed Combination Containing Pollen Extract Plus Teupolioside, in the Management of LUTS in Patients with Benign Prostatic Hypertrophy: A Pilot Study
- Extract from Cucurbita pepo improves BPH symptoms without affecting sexual function: a 24-month noninterventional study
- Aquablation vs. holmium laser enucleation of the prostate for benign prostatic hyperplasia: a 150-patients prospective comparative multicenter study
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.