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There is A Relationship between Inefficiency of External Urethral Sphincter and BPH? The Growth Factor and Pharmacological – Phytotherapy Role: The Inversion of The Classic Paradigm as Hypothesis of Work

Mauro Luisetto

Annals of Urology & Nephrology, 2025

Abstract

Aim of this work is to observe the indirect role played by external urethral sphincter in the development of BPH.There is any correlation between the reduced efficiency of this sphincter and prostate benign hyperplasia?The inefficiency of the external urethral sphincter needs an additional work by the upper prostatic urethra.This process can increase the autocrine and paracrine effect of the growth factor that can contribute to BPH.Can this move to be added to the hormonal effect played by androgen?And if confirmed this pathological process can have therapeutic implication?All these phenomena are analyzed to verify the hypothesis.

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