Erosive Ösophagitis: Zastaprazan ist Esomeprazol nicht unterlegen
Abstract
Die leitliniengerechte Therapie der erosiven Ösophagitis auf der Grundlage einer gastroösophagealen Refluxkrankheit besteht in der Einnahme von Protonenpumpeninhibitoren (PPI). Der Kalium-kompetitive Säureblocker Zastaprazan hemmt die H+/K+-ATPase wirksam und bietet zahlreiche Vorteile gegenüber den konventionellen PPI. Nach vielversprechenden Phase-1- und Phase-2-Ergebnissen durchlief der Wirkstoff nun eine Phase-3-Prüfung. Publication History Article published online: 11 September 2025 © 2025. Thieme. All rights reserved. Georg Thieme Verlag KG Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
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