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Analysis of clinical characteristics and risk factors for digestive system manifestations in rheumatic diseases

Di Zhu, Yuqing Hao

Srpski arhiv za celokupno lekarstvo, 2026

326 participants

Abstract

Introduction/Objective. The objective of the paper was to explore the risk factors and prediction models of digestive system complications in patients with rheumatic diseases. Methods. This case-control retrospective study enrolled 326 patients with rheumatic diseases (163 with digestive system involvement and 163 without), collecting demographic data, laboratory parameters (liver enzymes, lipid profiles, etc.), and disease types (rheumatoid arthritis, connective tissue diseases, gout, etc.). Potential variables were screened through univariate analysis, with independent risk factors subsequently identified using multivariate logistic regression analysis. Results. Univariate analysis revealed significantly higher proportions of males (35% vs. 20.2%, p = 0.003), alcohol consumption history (23.9% vs. 14.7%, p = 0.035), triglyceride (TG) (1.59 vs. 1.13 mmol/L, p 1.6 mmol/L, necessitating targeted intensive monitoring and clinical intervention.

How strong is the evidence?

Evidence Hub reads this as a case-control, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 326 participants or records.

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