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Current Epidemiological Status and Antibiotic Resistance Profile of Urinary Tract Infection

Muddasir Khan, Syed Hussain Shah, M. Abdullah, Muhammad Salman, Fawad Hayat, Raheela Sarwar, N. Hassan, Sohail Ahmad Jan et al.

Journal of Bioresource Management, 2022

2 citations

Abstract

With a longitudinal (2020–2021) completion, a set of 300 urine samples of individuals suspected of UTI was characterized based on the biochemical analysis and Kirby Bauer's disc diffusion method. Throughout, a total of 167 samples revealed UTI positivity by obtaining bacterial growth. Reporting that E. coli (69.4 %) was the most dominant when compared with Klebsiella (14.3 %), Proteus (5.9 %), S. aureus (4.7 %), P. aeruginosa (3.5 %), and Enterobacter (1.7 %), respectively. Gender-wise discrimination showed that E. coli was highly distributed among female (50.2 %) patients. A prominent percentage of E. coli (41.9 %) was found in the age group between 21-40 years. Isolates of E. coli represented the highest degree of resistance to Amoxicillin and Ceftriaxone (85.3 %), while highly sensitive to Amikacin, and Tazobactam (94.8 %). S. aureus was found highly resistant to Amoxicillin, Levofloxacin, Sulbactam, and Doxycycline (75 %), while highly sensitive to Meropenem, and Cefotaxime (100 %). Proteus spp. was found highly resistant to Sulbactam, and Cefotaxime (100 %), while highly sensitive to Tazobactam (100 %). Enterobacter was found highly resistant to Gentamicin (100 %), while highly sensitive to Aztreonam (100 %). Klebsiella was found highly resistant to Levofloxacin, and Doxycycline (91.6 %), while highly sensitive to Amikacin, Tazobactam, Gentamicin, and Cefoxitin (75 %). P. aeruginosa was found highly resistant to Nalidixic acid (100 %), while highly sensitive to…

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