Association between lifestyle, multiple chronic conditions, mental health status and the severity of lower urinary tract symptoms/benign prostatic hyperplasia in Chinese elderly
Abstract
Background and objective The etiology and pathogenesis of lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH) are complex, and understanding of factors related to symptom severity can improve the disease prognosis. The aim of this study was to explore the association between LUTS/BPH severity and lifestyle, multiple chronic conditions (MCC), and mental health status in Chinese elderly individuals, and to provide a reference for developing comprehensive intervention measures. Methods A total of 806 patients aged 60 and above with LUTS/BPH were divided into mild and moderate-to-severe groups based on IPSS assessment. All participants completed data collection on general demographics, clinical characteristics, lifestyle factors, MCC, and mental health status (including anxiety, depression, and sleep quality). A binary logistic model was employed to investigate the influence of lifestyle, MCC, and mental health status on LUTS/BPH severity. Results The moderate-to-severe group had significantly higher rates of unhealthy lifestyle habits, MCC, and mental health problems compared to the mild group. After adjusting for confounders (such as age, disease duration, prostate volume, total prostate-specific antigen, C-reactive protein, post-voided residual urine, urea nitrogen, etc.), current smoking (OR = 1.995, 95%CI:1.270–3.134), unhealthy dietary habits (OR = 1.590, 95%CI: 1.059–2.386), and lack of active exercise (OR = 1.996, 95%CI:1.274–3.127) were positively…
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