Meta-analysis of moxifloxacin in the treatment of domestical community-acquired pneumonia
Abstract
Objective To conduct a meta-analysis on the clinical trails of moxifloxacin for domestical community-acquired pneumonia and evaluate its outcome.Methods Related literature concerning clinical trials of moxifloxacin in treating community-acquired pneumonia published domestically from 2002 to 2010 were retrieved.Meta analysis on the selected literature was conducted by means of Review Manager 4.2 software.Results A total of 19 clinical trials were included in our study(homogeneity test χ2=0.30,P0.05),thus a fixed effect model was applied.Compared with the control group,moxifloxacin has a higher total effective rate with the odds ratio at 1.94 and 95% confidence interval at 1.32～2.84(P0.05).Conclusion Moxifloxacin can be used as an option in the treatment of community-acquired pneumonia.
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Evidence Hub reads this as a meta-analysis. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.
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