Quincke’s edema associated with moxifloxacin therapy in communityacquired pneumonia: a case report
Abstract
Background: Angioedema, also known as Quincke’s edema, is an acute hypersensitivity reaction characterized by sudden swelling of the skin, subcutaneous tissues, and/or mucous membranes. Drug-induced angioedema is uncommon but potentially life-threatening.
Case Presentation: We report the case of a 55-year-old man with community-acquired pneumonia who developed angioedema during moxifloxacin therapy. The patient initially presented with fever, productive cough, left-sided chest pain, and dyspnea. His medical history was significant for arterial hypertension, treated with lisinopril 5 mg orally once daily. Laboratory investigations revealed elevated liver enzymes, increased creatine kinase levels, and mild renal impairment. On the seventh day of hospitalization, the patient developed acute angioedema, which was successfully treated with intravenous dexamethasone, heparin, and furosemide.
Conclusion: Clinicians should remain vigilant for angioedema in patients receiving fluoroquinolones, particularly when concomitant angiotensin-converting enzyme (ACE) inhibitors are used. Early recognition and prompt management are essential to prevent serious complications.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Structural and topological analysis of thiosemicarbazone-based metal complexes: computational and experimental study of bacterial biofilm inhibition and antioxidant activity
- Toward better cures for Mycobacterium abscessus lung disease
- Challenges for global antibiotic regimen planning and establishing antimicrobial resistance targets: implications for the WHO Essential Medicines List and AWaRe antibiotic book dosing
- Design, Synthesis and In vitro Antitubercular Effect of New Chalcone Derivatives Coupled with 1,2,3‐Triazoles: A Computational Docking Techniques
- Upregulation of pmrA, pmrB, pmrC, phoQ, phoP, and arnT genes contributing to resistance to colistin in superbug Klebsiella pneumoniae isolates from human clinical samples in Tehran, Iran
- Whole-genome sequencing of clinical isolates of Citrobacter Europaeus in China carrying blaOXA−48 and blaNDM−1
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.