Chlamydia Abortus-Induced Pneumonia with Psychiatric Symptoms and Pneumomediastinum: A Case Report
Abstract
Bing Ding,* Zengkai Xu,* Youtang Li, Zhiyi Ma Longyan First Affiliated Hospital of Fujian Medical University, Longyan, Fujian, 364000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhiyi Ma, Longyan First Affiliated Hospital of Fujian Medical University, No. 105 Jiuyi North Road, Longyan, Fujian, 364000, People’s Republic of China, Email [email protected]: Chlamydia abortus is a zoonotic pathogen that commonly causes abortion, pelvic inflammatory disease, or septicemia during pregnancy in humans. It can occasionally lead to pneumonia.Case Presentation: We report a 35-year-old male with pneumonia complicated by psychiatric symptoms and pneumomediastinum. Initial treatment with cefotaxime and piperacillin-tazobactam failed. On admission, chest CT revealed bilateral pulmonary inflammation, pneumomediastinum, and cervical subcutaneous emphysema. Bronchoalveolar lavage fluid underwent Targeted Next-Generation Sequencing, identifying Chlamydia abortus. Treatment with doxycycline and moxifloxacin led to resolution of fever, psychiatric symptoms, and pulmonary lesions. The patient continued oral doxycycline post-discharge, and follow-up CT showed near-complete recovery.Conclusion: Chlamydia abortus infection can cause pneumonia with psychiatric symptoms, pneumomediastinum, and cervical emphysema—complications not previously reported. Targeted Next-Generation Sequencing (Targeted NGS) plays a crucial role in the early and precise…
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