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Curative effect of moxifloxacin on malignant tumor combined with community-acquired pneumonia

Weihua Wang, Yihua Zheng, Ai-xin Zhou, Xuemei Lin, Juann-hua Mao, Zhenhua Li

Chinese Journal of Asthma, 2011

118 participants

Abstract

Objective To research the curative effect and security of moxifloxacin on malignant tumor with community-acquired pneumonia.Methods 118 patients with malignant tumor combined with community-acquired pneumonia were randomly divided into treatment group (60 cases) and control group (58 cases).The treatment group and control group were treated with moxifloxacin and levofloxacin,respectively.Then the curative effect and security were observed.Results The total effective rates were 88.3% and 62.1%,cure rates were 48.3% and 34.5% in treatment group and control group,respectively.Totally,the two groups isolated 65 bacterium.The bacterial clearance rates were 87.9% and 62.5%,and the incidence of adverse events were 5.0% and 10.3% in treatment group and control group,respectively ( P <0.05).Conclusions This study suggests that moxifloxacin is an effective and safe drug with high bacterial clearance rate for treating cancer patients with community-acquired pneumonia.

Key words:

Moxifloxacin; Levofloxacin; Malignant tumor; Community-acquired pneumonia

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