Clinical observation on moxifloxacin treating elderly patients in community acquired pneumonia
Abstract
Objective To evaluate the clinical efficacy and toxic side effect of moxifloxacin in the treatment of elderly patients with community acquired pneumonia(CAP).Methods 196 elderly patients with CAP were reviewed from June 2010 to June 2012 in our hospital,which were randomly divided into 98 cases of moxifloxacin group(test group) and 98 cases of cefoperazone sulbactam group(control group),to evaluate its clinical efficacy and toxic side effect.Results The total effective rate was 90.8% in the test group and 69.6% in the control group respectively(P = 0.34);The cure rate was 81.6% in the test group and 60.2% in the control group respectively(P = 0.38);The bacterial clearance rate was 86.5% in test group and 60.2% in the control group respectively(P = 0.04);The incidence of adverse events was 6% in the test group and 4% in the control group respectively(P = 0.7).Conclusion Moxifloxacin have satisfactory effects in treating CAP,with low toxic side effect,is worthy to recommand its clinical applycation.
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