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Trend of Use of Quinolone Antibiotics in Community-Acquired Pneumonia

Kadir Burak Akgün, Emel Ceylan, Mehmet Karadağ, Merve AYIK TÜRK

Mediterranean Journal of Infection Microbes and Antimicrobials, 2025

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Abstract

Introduction: Quinolone group antibiotics are frequently used in the treatment of community-acquired pneumonia (CAP).There have also been rising safety concerns related to quinolone usage.In this study, we investigated physicians' tendencies to prescribe quinolones when managing outpatient pneumonia treatment and the factors influencing this decision. Materials and Methods:Physicians were asked to participate in a survey consisting of 20 questions.They were queried about the antibiotic groups they most frequently prescribe for outpatient treatment in cases of CAP, the specific type of quinolone they most commonly used, their opinions on the effects and side effects of quinolones through Likert-type survey, and the clinical scenarios that lead them to prescribe quinolones.In addition, a comparison was made between pulmonologists and other specialists on these factors.Results: A total of 16.29% of physicians primarily prescribed quinolones.The most preferred quinolone was moxifloxacin (50%).In cases of treatment failure, physicians were more likely to opt for hospitalization and a broad-spectrum antibiotic treatment approach (78.09%).Pulmonologists were more likely to prescribe quinolones in cases of unresponsiveness to previous beta-lactam therapy and complicated pneumonia than nonpulmonologists (p=0.013,p=0.044, respectively).Pulmonologists placed more importance on the tendinitis side effect compared to nonpulmonologists (p=0.019).Among the clinical factors, the previous…

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