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Trend of Use of Quinolone Antibiotics in Community-Acquired Pneumonia

K. Akgün, Emel Ceylan, M. Karadağ, Merve Ayık Türk

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2024

2 citations

Abstract

Objectives: Quinolone group antibiotics are used frequently in the treatment of community-acquired pneumonia. In addition, safety concerns regarding quinolones are also on the rise. This study aimed to investigate physicians' tendencies to prescribe quinolones when managing outpatient pneumonia treatment and the factors influencing their decisions. Methods: Physicians were asked to participate in a survey consisting of 20 questions. They were queried about the antibiotic groups they most frequently use when prescribing outpatient treatment for community-acquired pneumonia, the specific type of quinolone they most commonly use, their opinions on the effects and side effects of quinolones through Likert-type questions, and the clinical scenarios that lead them to prescribe quinolones. Additionally, a comparison was made between pulmonologists and other specialists. Results: A total of 16.29% of physicians primarily prescribed quinolones. The most preferred quinolone was moxifloxacin (50%). In cases where treatment failed, physicians were more likely to hospitalize patients and approach broad-spectrum antibiotic therapy (78.09%). Pulmonologists were more likely to prescribe quinolones in cases of unresponsiveness to previous beta-lactam therapy and complicated pneumonia than non-pulmonologists (p=0.013, p=0.044, respectively). Pulmonologists placed more importance on tendinitis side-effect compared to non-pulmonologists (p=0.019). Among the clinical factors, the previous use of…

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