The classic Chinese medicine weijing decoction as a complementary intervention for respiratory diseases: A systematic review and meta-analysis
Abstract
Background: The incidence of pulmonary diseases remains unacceptably high, underscoring the need for improved therapeutic strategies. The current therapeutic landscape, largely reliant on antibiotics and hormonal agents, is constrained by growing challenges such as drug resistance, significant toxicity profiles, and prolonged disease courses. As a time-honored TCM prescription, Weijing Decoction (WJD) is widely administered for respiratory ailments. However, a critical appraisal of the existing literature reveals a paucity of high-quality evidence. Research to date has largely been confined to anecdotal case reports or preliminary investigations with limited sample sizes, resulting in a lack of systematic assessment on the combined efficacy and safety of WJD and modern medical interventions.
Objective: This study aimed to systematically evaluate and meta-analyze the therapeutic efficacy of Weijing Decoction (WJD) in the management of respiratory diseases, including chronic obstructive pulmonary disease (COPD) and pneumonia.
Methods: A comprehensive literature search was conducted across six electronic databases, including both international and Chinese-language databases, to identify randomized controlled trials (RCTs) evaluating the efficacy of WJD in the treatment of COPD and pneumonia. Data on primary outcomes, including the overall clinical efficacy rate, C-reactive protein (CRP) levels, and Traditional Chinese Medicine Syndrome Scores, were extracted and synthesized…
How strong is the evidence?
Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 1,315 participants or records.
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