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Efficacy and safety of antibiotic and invasive management of lung abscess: A systematic review

Helena Ibsen, Victor Næstholt Dahl, Katrine Lawaetz Kristensen, Anzhela Tsorokh, Elisabeth M. Bendstrup, Andreas Fløe, Søren Sperling

Respiratory Medicine, 2025

4 citations

Abstract

Lung abscess (LA) is a severe, necrotizing infection of the lungs characterized by the formation of one or more cavities within the lung tissue [1]. It commonly develops as a complication of pneumonia, particularly in individuals with pre-existing chronic pulmonary conditions, such as chronic obstructive pulmonary disease (COPD) or in patients with predisposing factors, including alcohol abuse or use of sedative agents [2,3]. Despite advances in medical care, LA remains associated with considerable morbidity and mortality, and evidence to guide optimal treatment remains limited [4].

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