Bacteriological Profile and Antibiotic Sensitivity Pattern Among Ventilator-Associated Pneumonia Patients in Intensive Care Unit of NIDCH and Factors Contributing Antibiotic Resistance
Abstract
Background: Ventilator-associated pneumonia (VAP) is the most frequent intensive careunit (ICU) acquired infection and is associated with significant mortality, morbidity andcosts. The etiology and antimicrobial susceptibility pattern of VAP is variable and thereis scarcity of data. So, this study aimed to track the bacteriological profile of pneumoniaand their current local antibiotic susceptibility pattern among ICU patients (VAP) and toidentify factors responsible for antibiotic resistance.
Objective: To determine the spectrum of bacteria that causes Ventilator-associated pneumonia (VAP) by tracheal aspirates culture and the antibiotic sensitivity admitted in ICU.
Materials and Methods: This was a cross-sectional descriptive type of observational study was conducted at the National Institute of Diseases of the Chest and Hospital (NIDCH) from 01.07.2019 to 30.06.2020. Total 46 diagnosed cases of VAP were included in this study. Following informed written consent, clinical and demographical history were taken, physical examination and relevant investigations were done for all patients. In all cases, ethical issues and health issues were maintained properly and collected data were analyzed by SPSS 23.
Results: Among 46-VAP patients, average age of the study population was 54.26±12.01 SD (years), ranging from 31 to 90 years. Male female distribution showed male predominance with 76.1% male and 23.9% female. Regarding risk factors, 78.3% had history of smoking, 60.9% had…
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Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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