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P15 The main aetiological factors of lung damage in severe pneumonia and sepsis in military servicemen: retrospective analysis for 2023

O. Viltsaniuk, V. Syvak, Tatiana M Lysak, N. Sokolovska, Martyniuk Viktoria, O. Viltsaniuk

JAC-Antimicrobial Resistance, 2024

Abstract

Abstract Background Today, the problem of pulmonary pathology is very relevant in Ukraine, as it is not always possible to provide timely and high-quality medical care owing to the Russian invasion of Ukraine. Objectives To analyse the types of the main aetiological factors of lung pathology and their susceptibility to different groups of antimicrobial agents used at different stages of treatment of these patients. Materials and methods Microbiological studies of 36 case histories of severe patients who were inpatients in the pulmonology department of the Military Medical Centre were analysed. Results The main diseases that caused lung pathology were community-acquired pneumonia (44%), septic pneumonia (29%) and nosocomial pneumonia (27%). When studying the extent of lung involvement, the most common was involvement of four and five lobes of the lungs, which accounted for 61% of all cases, and the most common complication was exudative pleurisy (57%). In the course of studying the microbiological characteristics of pathogens, a monoculture was isolated in 80% of cases, in 12% of cases there was a combination of Staphylococcus aureus and Klebsiella pneumoniae, and in 8% of cases S. aureus, K. pneumoniae and Enterobacter were identified. S. aureus and K. pneumoniae were most often isolated from sputum and pleural fluid. Susceptibility testing showed that in the vast majority of cases S. aureus was susceptible to meropenem, linezolid, cefepime, cefoperazone, ciprofloxacin and…

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