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Pharmacotherapeutic Assessment of Three Major Infectious Disorders in District Abbottabad and Haripur

Aamna Shah, Umme Salma, Nargis Aman, Muhammad Ali, Raahim Ali, Salwa M. A. Dahesh, Sumbul Qamar, . Moeen et al.

The Open Public Health Journal, 2026

300 participants

Abstract

Objective The current study was focused on the assessment of pharmacotherapeutic practices and potential drug-drug interactions among patients suffering from three major infectious disorders, including Typhoid fever, Pneumonia, and urinary tract infection (UTI). Methodology The data collection process included 300 patients (with 100 cases belonging to each disease) visiting DHQ Hospital, Haripur, and Jinnah International Hospital, Abbottabad. Comprehensive patient profiles, including disease prognosis, diagnosis, and therapeutic management, were carefully assessed for each patient, along with their comparison with standard therapeutic guidelines for identification of potential drug-associated risks. Analysis was performed based on sex-disaggregated comparison to critically evaluate the variability regarding disease prevalence, therapeutic management, and therapeutic outcomes among male & female patients. Results Typhoid fever, caused by Salmonella Typhi (most frequently transmitted via contaminated food or water), was found to be more prevalent in females (70%) than male candidates (30%), though the majority of the sample (80%) was based on the adult population. Most of the cases belonged to the Abbottabad region, and the widal/typhidot test was considered the major diagnostic test. Therapeutic management was mainly comprised of antibiotics together with analgesics/antipyretics, anti-ulcer drugs, antiemetics, electrolytes, and vitamins. Parenteral and oral routes of…

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