A comparative study of efficacy of tamsulosin monotherapy vs. combined (Solifenacin + tamsulosin) in treatment of ureteric stent related symptoms
Abstract
Ureteric Double J stenting is the most common in endourological practice. The double-J stent, which is the most common form of ureteral stent, is used in obstructive pyelonephritis, intolerable acute renal colic, ureteral edema, ureter perforation following endoscopic procedures. Post stenting commonly reported symptoms include flank pain, haematuria, dysuria, frequency, and urgency. Tamsulosin acts as a selective inhibitor of α1A/1D and Solifenacin acts as a muscarinic receptor antagonist have been used in alleviating the symptoms and have been proved effective. Objective: To study the efficacy of tamsulosin monotherapy vs. combined (solifenacin + tamsulosin) in treatment of ureteric stent related symptoms.Methodology: The prospective control study conducted in R.L. Jalappa Hospital, Tamaka, Kolar. The study included 60 subjects divided on even and odd method with 30 in each group with a period of 3 months. The subjects in group A received oral Tamsulosin of 0.4mg once daily and group B received oral Tamsulosin+ solifenacin (0.4mg+6mg) once daily. The subjects were observed for post-operative complications like flank pain, dysuria and sexual dysfunction. The dysuria was calculated according to Boysarky score and UTI with grading. The data were collected and analysed statistically.Results: The most common age group of presentation of subjects were less than 40 years i.e 22(36.66%) with next common group was 51-60 years accounting 15(25%) with mean age being 45.5 years. The…
Read the paper
Related studies
- Sarcopenia, sarcopenic overweight/obesity and risk of cardiovascular disease and cardiac arrhythmia: A cross-sectional study
- Workplace Violence Is Associated With Impaired Work Functioning in Nurses: An Italian Cross-Sectional Study
- Vagus Nerve Dysfunction in the Post-COVID-19 Condition: a pilot cross sectional study
- Association Between Metabolic Associated Fatty Liver Disease and Chronic Kidney Disease: A Cross-Sectional Study from NHANES 2017–2018
- Efficacy and safety of solifenacin succinate 10 mg once Daily: A multicenter, phase III, randomized, double-blind, placebo-controlled, parallel-group trial in patients with overactive bladder
- Association between triglyceride glucose‐body mass index and hypertension in Chinese adults: A cross‐sectional study
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.