Comparison of Behaviour Therapy versus Combination Therapy, Solifenacine with Behaviour Therapy in the Management of the Nocturnal Enuresis
Abstract
Background: Nocturnal enuresis (NE), known as bedwetting, is a common problem with psychosocial challenges, if not properly managed, defined as the involuntary urine leakage during sleep. Objective: Outcomes comparison in the management of behaviour therapy VS combination therapy, solifenacin with behavioural-therapy in children with bedwetting. Study Design: Randomized-controlled trial. Settings: Departments of Paediatric Urology, Children's Hospital, Faisalabad Pakistan. Duration: Six months (01-04-2025 to 30-09-2025). Methods: The study was conducted with a comparison of two groups: group A consisted of patients with behaviour therapy management alone in NE, while group B consisted of patients managed with combination therapy, Solifenacin with behaviour therapy. Results: The mean wet nights were decreased in group A (only behaviour therapy) to 2.1 ± 1.4 nights/week, while in group B (1.3 ± 1.1 nights/week) were documented when patients took solifenacin with behaviour therapy. The reduction was significantly greater in the solifenacin group compared to behaviour-therapy (p=0.02). Treatment response of group-A 35% achieved complete recovery, 40% had partial recovery, and 25% had no recovery. In comparison with group B, solifenacin with behaviour therapy group have 50% complete recovery, 35% achieving partial recovery, and 15% showed no recovery. Although the complete recovery rate was higher in group B, the difference did not have strong statistical significance (p = 0.08).…
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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.
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