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ไวบกรอน: ยาตวใหมสำหรบรกษาภาวะกระเพาะปสสาวะบบตวไวเกน

Napassorn Rungsilp

Thai Journal of Hospital Pharmacy, 2026

Abstract

Overactive bladder is a common condition among older adults and has an impact on quality of life. Current standard treatment includes anticholinergic agents; however, these medications are associated with various adverse effects that may limit treatment adherence. Consequently, newer therapeutic agents with improved efficacy and safety profiles have been developed, including vibegron, a β3-adrenergic receptor agonist. Based on evidence from comparative literature reviews, vibegron was found to significantly reduce urinary frequency, urgency episodes, and urgency urinary incontinence with statistically significant improvements. Regarding safety, adverse event rates were low and comparable to the placebo. Therefore, vibegron is effective and safe for the management of overactive bladder.

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