From Research to Practice: The Role of Mirabegron in Managing Overactive Bladder
Abstract
Millions of people in the world suffer from Overactive bladder (OAB). It is characterized by urinary incontinence, increased frequency, and nocturia, which leads to a compromise in the quality of the patient’s life. Traditional treatments comprised of antimuscarinic agents have limitations due to the side effects and reduced long-term effectiveness which creates a demand for alternative therapies. Treatment strategy for overactive bladder (OAB) has changed from antimuscarinics to β3-adrenergic receptor agonists after the discovery of mirabegron in 2012. This review examines the effectiveness of mirabegron in OAB patients and its integration into clinical practice. New advances in disease management mostly depend on the appropriate use of clinical data in guidelines for clarity. This is evident in OAB management with Mirabegron. The landscape has changed, providing new options for healthcare professionals. This review discusses the latest data on mirabegron use, efficacy, safety, cost-effectiveness, and its potential use in combination therapies. In addition to its position in OAB management, the futuristic use of this β3-adrenergic receptor agonist will also be explored.
Read the paper
Related studies
- Sarcopenia, sarcopenic overweight/obesity and risk of cardiovascular disease and cardiac arrhythmia: A cross-sectional study
- Workplace Violence Is Associated With Impaired Work Functioning in Nurses: An Italian Cross-Sectional Study
- Vagus Nerve Dysfunction in the Post-COVID-19 Condition: a pilot cross sectional study
- Association Between Metabolic Associated Fatty Liver Disease and Chronic Kidney Disease: A Cross-Sectional Study from NHANES 2017–2018
- Efficacy and safety of solifenacin succinate 10 mg once Daily: A multicenter, phase III, randomized, double-blind, placebo-controlled, parallel-group trial in patients with overactive bladder
- Association between triglyceride glucose‐body mass index and hypertension in Chinese adults: A cross‐sectional study
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.