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The Impact of Psychological Interventions on Functioning in the Context of Borderline Personality Disorder Features for Adolescents and Young Adults: A Systematic Review and Meta-Analysis

Brandrett BD, Gajwani R

Early intervention in psychiatry, 2026

657 participants · 1 citation

Abstract

Objective: Adolescents recruited from clinical samples with borderline personality disorder (BPD) often experience significant functional impairment across multiple domains. Evidence indicates that borderline personality features emerging before adulthood can predict long-term difficulties and may worsen over time. However, the role of assessment methods and the impact of psychological interventions on functional outcomes remain unclear.

Methods: A systematic review and meta-analysis of randomised controlled trials (RCTs) was conducted to evaluate the impact of psychological interventions on functioning in adolescents and young adults with BPD features. Four databases (PsycINFO, Medline, Embase and CINAHL) were searched up to June 2023.

Results: From 1859 identified studies, seven trials (N = 657) met the inclusion criteria. Across studies, psychological interventions were associated with improvements in functioning from baseline to both post-treatment and final follow-up. However, when comparing specialised psychological interventions to generalist treatment as usual (TAU), differences were not statistically significant. Effect sizes were small at post-treatment (SMD = 0.13, 95% CI = [-0.05, 0.31]) and remained small at final follow-up (SMD = 0.12, 95% CI = [-0.08, 0.33]). Substantial heterogeneity was observed across studies, and risk of bias was noted in several trials, with only two studies rated as low risk.

Conclusions: The findings suggest that both specialised…

How strong is the evidence?

Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 657 participants or records.

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