News in diabetology 2016
Abstract
The field of diabetes is constantly evolving, with numerous new molecules reaching the market in the treatment of type 2 diabetes. Paradoxically, this drug jungle is difficult for the primary care physician and can lead to therapeutic inertia. After the beneficial effect of empagliflozin on cardiovascular outcomes in the EMPA REG Outcome trial in 2015, liraglutide also shows cardiovascular benefits in high risk patients with type 2 diabetes. Therefore, these two studies, led to new recommendations by the Swiss Society for Endocrinology and Diabetes, by notably favouring the prescription of these molecules to type 2 diabetic patients in secondary prevention, after metformin.
La diabétologie est une discipline en pleine évolution, notamment suite à l’apparition sur le marché de nombreuses nouvelles molécules qui enrichissent la panoplie des traitements possibles dans le diabète de type 2. Ceci s’accompagne paradoxalement d’une plus grande difficulté pour le médecin traitant à se retrouver dans cette jungle thérapeutique, ce qui peut mener à une certaine inertie thérapeutique. Après l’étude EMPA REG Outcome en 2015, qui a montré un bénéfice cardiovasculaire chez les patients diabétiques de type 2 à haut risque cardiovasculaire pour l’empagliflozine, une autre molécule, le liraglutide, a elle aussi montré un bénéfice cardiovasculaire chez les patients diabétiques de type 2 à haut risque. Ainsi, ces deux études ont mené à de nouvelles recommandations sur le plan suisse.
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