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Bolstering your armamentarium with SGLT2 inhibitors

Novak LM, Kruger DF

The Nurse practitioner, 2017

Abstract

Sodium-glucose cotransporter-2 inhibitors have a unique mechanism of action in the kidneys that causes glucosuria, which lowers plasma glucose. They are also associated with reduced body weight and BP, and a low incidence of hypoglycemia. This article reviews the pharmacologic profiles and clinical implications of canagliflozin, dapagliflozin, and empagliflozin.

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