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Hypothetical Role of Multiwavelength Diode Laser (755, 808, and 1064 nm) in Addressing Bony Resorption in Facial Aging: A Clinical Commentary

Wan J, Yoon SE, Song JK, Lim T, Kim JH, Kim S, Yi KH

Journal of cosmetic dermatology, 2025

2 citations

Abstract

Background: Facial aging involves not only soft tissue laxity but also progressive bony resorption, particularly in the maxilla and mandible. Current non-invasive aesthetic modalities primarily target soft tissues, neglecting skeletal changes that contribute to volume loss and structural descent.

Objective: To propose the hypothetical role of multiwavelength diode laser (MWDL) in stimulating osteogenesis via controlled thermal delivery to the periosteum, offering a novel, non-invasive strategy for counteracting facial bone resorption.

Methods: This clinical commentary discusses MWDL's mechanism-targeting the periosteal layer using 755, 808, and 1064 nm wavelengths (N.CORE 3D (previous version of Fortra), Classys Inc., Seoul) to deliver 43°C-46°C heat. A case study of a 70-year-old female receiving 16 sessions over 4 years was included. Cortical bone thickness was measured pre- and post-treatment using dental radiographs.

Results: Modest increases in cortical bone thickness were observed: from 3.4 to 3.51 mm (left) and from 3.14 to 3.37 mm (right), suggesting possible periosteal osteogenic stimulation.

Conclusion: MWDL may represent a promising adjunct to soft tissue rejuvenation by addressing age-related skeletal decline. While early findings are encouraging, controlled trials are needed to validate efficacy, optimise protocols, and define long-term safety.

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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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