Osteoblastoma of the Hamate: A Case Report
Abstract
Introduction: Osteoblastomas are rare, benign, osteoid-producing primary bone tumors that typically occur in adolescents and young adults. They constitute only 1% of all bone tumors and are exceptionally rare in the hand and wrist. Carpal bone involvement is exceedingly uncommon, with only 9 cases reported in the literature involving the hamate. This case is important to report because the occurrence of this neoplasm in the fifth decade of life is extremely rare, making it one of the very few reports of hamate osteoblastoma in late adulthood.
Case report: A 51-year-old male presented with a 2½ year history of persistent pain and progressive swelling over the dorsal aspect of the ulnar side of the left wrist. The pain was unrelieved by painkillers and worsened after minor trauma. Clinical examination revealed a firm, tender swelling accompanied by joint stiffness. Radiographs showed a well-defined lytic lesion with a sclerotic rim in the hamate, whereas further imaging demonstrated blood-fluid levels. Histopathology confirmed the diagnosis of osteoblastoma. He underwent extended curettage followed by filling the defect with an autologous cancellous bone graft. The patient experienced rapid symptomatic relief, returned to routine activities with full range of motion, and showed no signs of recurrence at the 18-month follow-up.
Conclusion: This case report demonstrates that despite its rarity, osteoblastoma should be considered in the differential diagnosis of persistent,…
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Irisin Enhances Osteoblast DifferentiationIn Vitro
- Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo
- Interaction between Schwann Cells and Osteoblasts In Vitro
- Administration of cinnamaldehyde promotes osteogenesis in ovariectomized rats and differentiation of osteoblast in vitro
- The Effect of the Major Components of Fructus Cnidii on Osteoblasts In Vitro
- Estrogen depletion alters osteogenic differentiation and matrix production by osteoblasts in vitro
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.