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Rare Osseous Metaplasia in a Hyperplastic Gastric Polyp

Conder E, Brenner A, Campbell D, Rueckert J, Brazel E

ACG case reports journal, 2026

Abstract

Gastric hyperplastic polyps are often discovered unexpectedly during endoscopy, usually arising in the antrum. Polypectomy is recommended when findings such as size >1 cm, dysplasia, ulceration, or iron deficiency anemia are present. We report a rare case of osseous metaplasia in a pyloric polyp causing obstructive symptoms that resolved following polypectomy, including early satiety, abdominal pain, and bloating. Fewer than 10 cases of osseous metaplasia in gastric polyps have been reported, and limited data suggest it is benign. This case describes potential predisposing factors, summarizes proposed mechanisms, and emphasizes the need for further research to clarify clinical significance and formal management.

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