Juvenile Rectal Polyp Exhibiting Osseous Metaplasia: A Case Report
Abstract
A 10-year-old boy presented with painless rectal bleeding. No fever or weight loss was reported. He had no history of constipation. Ileocolonoscopy revealed a single 2 cm pedunculated polyp in the distal rectum, which was removed endoscopically. Histological examination demonstrated polypoid tissue with focal ulceration characterized by an inflamed lamina propria containing dilated, branched, and hyperplastic crypts. Higher-power microscopy revealed mature bony trabeculae within the lamina propria. No dysplasia was observed. Osseous metaplasia is generally regarded as clinically and prognostically insignificant and is typically an incidentalhistological finding. We report an extremely rare case of heterotopic bone formation in a juvenile rectal polyp and review recent literature on this phenomenon.
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Irisin Enhances Osteoblast DifferentiationIn Vitro
- Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo
- Interaction between Schwann Cells and Osteoblasts In Vitro
- Administration of cinnamaldehyde promotes osteogenesis in ovariectomized rats and differentiation of osteoblast in vitro
- The Effect of the Major Components of Fructus Cnidii on Osteoblasts In Vitro
- Estrogen depletion alters osteogenic differentiation and matrix production by osteoblasts in vitro
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.