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Management of Peripheral Cemento-Ossifying Fibroma

Sabesan M, Rajan ST, Nirmala V, Ravindran DM, Sharon B

Cureus, 2026

Abstract

Peripheral cemento-ossifying fibroma (PCOF) is a rare, reactive osteogenic neoplasm that presents as an epulis-like growth with unknown pathogenesis. This lesion commonly affects the younger generation. Frequently associated with the maxilla, it is more common in the anterior region. Here, we present a rare case of a 54-year-old male patient with a painless gingival swelling in the mandible for a period of one year. Prompt diagnosis through complete radiographic and histopathologic examination is critical for proper diagnosis of this lesion. Proper surgical removal with complete curettage is extremely important for the prevention of recurrence.

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