Brown algae fucoidan impact on osteoblast during osteogenesis: A narrative review
Abstract
Objective: This study is to provide insight into the possible therapeutic uses of fucoidan in treating alveolar bone resorption by analyzing the current literature. Methode: This paper conducted a literature study using the PubMed database, Google Scholar, ResearchGate, and BMC databases to find keywords related to fucoidan, herbal medicine, angiogenesis, and osteogenesis. Result: This narrative review uses data from PubMed, Google Scholar, and Researchgate to examine the possible advantages of fucoidan chemicals from brown algae, which can help with bone regeneration and angiogenesis by blocking the manufacture of osteogenic signals. Conclusion: Osteoblast differentiation, osteoclast activity regulation, and osteogenic marker expression can all be enhanced by Sargassum sp. fucoidan. Fucoidan has the additional ability to hasten the osteogenesis process and encourage the growth of new bone tissue.
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